Study Links Ibuprofen to Male Infertility

Study Links Ibuprofen to Male Infertility

Study Links Ibuprofen to Male Infertility

Researchers in Denmark and France have found that ibuprofen can trigger a condition called "compensated hypogonadism" that is otherwise observed in men with reproductive disorders.

The condition is normally seen in older men and smokers, and is caused by the body having to boost testosterone levels because normal production in the testes is insufficient.

Bernard Jégou, a senior author on the study at the French National Institute of Health and Medical Research, said that he believes that there is no problem in people taking ibuprofen to alleviate pain in the short term but he warns against taking the drug for months on end if it was not absolutely necessary.

The human brain compensates for testosterone deficiency by producing luteinizing hormone (LH), which sends a signal to the testicles to produce more testosterone.

The study only focused on a small group of participants, so more research will be needed before the affects of ibruprofen are fully established. Some took 1,200 milligrams of ibuprofen - commonly known as Advil or Motrin, among others - every day in two 600 mg doses over a six-week period, while others received a placebo.

Ibuprofen is good for a headache, but for male fertility not so much, a new study found. Each dose was 600mg, equivalent to three over-the-counter pills. No direct effect on fertility was shown, but the results of this initial study suggest that it warrants further investigation.

'Sheer chaos' as planes collide at Pearson airport
It was being towed by the airline's ground handling service provider at the time of the incident. One of the eyewitness Gustavo Lobo said to CBC News "It was chaos".

Winning Mega Millions ticket sold in Florida for $450 million jackpot
The identity of the victor was not immediately available, although the victor can not remain anonymous under Florida law. Most winners opt for cash options, which would be $281 million for Mega Millions and $358.5 million for Powerball.

Astronaut John Young Dead
In March 1965, he made his first flight as an astronaut, joining Gus Grissom on Gemini 3, the first manned flight of that program. It was the first time a piloted spacecraft was tested in space without previous orbital flights with nobody on board.

Pregnant women are increasingly advised to avoid ibuprofen during late pregnancy because it has been associated with increased complications for both mother and baby, including decreased amniotic fluid and potential heart problems in the baby.

But long-distance runners and athletes who regularly take ibuprofen during training or sports matches in order to ward off inflammation may want to keep an eye on the research.

To avoid these side-effects, doctors caution against taking Ibuprofen for more longer than ten days in a row, per the FDA's warning.

Researchers also found that those using the drug had developed hypogonadism, a form of sexual dysfunction.

The disorder was mild and temporary in the clinical volunteers, researchers told The Guardian newspaper in the United Kingdom. "Ibuprofen is a very useful drug for acute pain conditions, its benefits have been well proven, but it is important to consider that hypogonadism may be an additional risk factor that people need to watch for when taking the drug for a long time", he said.

Related news